The Zoloft should be administered once a day, morning or evening.
Zoloft capsules should be administered during the meal.
Initial treatment
Depression and OCD
The Zoloft treatment should be started at a dose of 50 mg/day.
Panic disorder, PTSD and social anxiety disorder
The treatment will be started at a dose of 25 mg/day. After a week, the dose will be increased to 50 mg once daily. This dosing regimen has been shown to reduce the frequency of early adverse characteristic of panic disorder.
Dosage adjustment
Depression, TOC, panic disorder, social anxiety disorder and PTSD
Patients do not meet a 50 mg dose, a dose increase is possible. Dose changes should be done by levels of 50 mg at intervals of at least a week, up to a maximum of 200 mg/day. Dose changes should not be carried out more than once a week, taking into account the elimination half-life of the Zoloft which is 24 hours.
The therapeutic effect can occur within 7 days. However, longer periods are usually required to obtain a therapeutic response, in particular for the clicks.
Maintenance
The dose in a long-term treatment must correspond to the minimum effective dose, dosage adjustments based on the individual therapeutic response.
Depression
A more long-term treatment may also be appropriate for the prevention of recurrence of major depressive episodes (EDM). In the majority of cases, the recommended dose for the prevention of recurrence of EDM is identical to that used during the current episode. Depressive patients must be treated on a sufficiently long period of at least 6 months to ensure the disappearance of symptoms.
Panic disorder and TOC
Continued treatment in panic disorder or the TOC must be reassessed regularly, as relapse prevention has not been demonstrated in these disorders.
Pediatric patients
Children and adolescents with obsessive compulsive disorder
Between 13 and 17: initial dose of 50 mg once a day.
Between 6 and 12 years: initial dose of 25 mg once a day. The dose may be increased up to 50 mg once a day after a week.
Insufficient response, a secondary increase of the dose is possible by levels of 50 mg over a period of several weeks if necessary. The maximum dose is 200 mg per day.
It must however take account of the generally lower weight of children compared to adults an increase beyond 50 mg dose. Dose changes should not be carried out at intervals of less than a week.
Efficiency is not demonstrated in major depressive disorder of the child.
No data is available in children under the age of 6 years (see also warnings and precautions of employment).
Use in the old topic
In the old subject, the dose must be carefully tailored because of the increased risk of hyponatremia (see warnings and precautions of employment).
Use in hepatic insufficiency
The use of Zoloft in patients with liver disease must be made with caution. Inadequate hepatic must receive lower or more widely spaced doses (see warnings and precautions of employment). The Zoloft should not be used in severe liver failure, given the lack of available clinical data (see warnings and precautions of employment).
Use in renal insufficiency
No dosage adjustment is necessary in the insufficient renal (see warnings and precautions of employment).
Observed in the interruption of the treatment by the Zoloft withdrawal symptoms
A brutal interruption must be avoided. In the case of the Zoloft treatment, the dose should be gradually reduced over a period of at least one to two weeks, to reduce the risk of withdrawal reactions (see warnings and precautions of use and adverse effects). If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, a resumption of the previously prescribed dose may be considered. Subsequently, the physician will continue to reduce the dose, but more gradual way.
Generic Zoloftzoloft without prescription
Sertraline hydrochloride (brand names Zoloft) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market in 1991. Sertraline is primarily used to treat major depression in adult outpatients as well as obsessive–compulsive, panic, and social anxiety disorders in both adults and children. In 2007, it was the most prescribed antidepressant on the U.S.
Wikipedia
Withdrawal symptoms observed in the judgment of the treatment by the sertraline
Withdrawal symptoms are frequently observed to the interruption of the treatment, especially if the case is brutal (see adverse reactions). In clinical studies, patients treated with sertraline, the impact of the reported withdrawal reactions was 23% in patients interrupting sertraline compared to 12% among those who continued treatment with sertraline.
The risk of withdrawal symptoms may depend on several factors, including the duration of treatment, dosage, and dosage reduction rates. The most frequently reported reactions are the following: Dizzy sensation disorders sensory (including paresthesias), disorders of sleep (including insomnia and intense dreams), agitation or anxiety, nausea and/or vomiting, tremor and headache. Generally, these symptoms are mild nature moderate; However, in some patients, their intensity can be severe. They generally occur in the first days following discontinuation of treatment, but have been reported rarely in patients who have forgotten a dose inadvertently. Generally, these symptoms are self-limiting and often disappear in two weeks, but can be more extended in some patients (2 or 3 months or more). Therefore, it is recommended to gradually reduce the dosage of sertraline during the interruption of the treatment over a period of several weeks or months, the needs of the patient (see topic dosage and administration).
Zoloft is manufactured in scored tablets of 25, 50 and 100 mg. Zoloft is usually taken once each day and may be taken with or without food.
Based on clinical studies, Zoloft is not believed to be addictive or habit-forming.
Take the missed dose as soon as you remember, unless it’s nearly time to take your next dose. Do not take extra Zoloft to make up the missed dose.
Drinking alcohol while taking ZOLOFT is not recommended.
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